Dr. Alexandre Cannillo

doctor in organic chemistry

 

 

Département de Chimie Moléculaire

Université Grenoble Alpes

301 rue de la chimie, Grenoble, France

 

e-mail: cannillo[a]synthetic.fr

 

 

Education

 

Ph.D. Organic Chemistry

ICSN CNRS, Gif-sur-Yvette, France

2010-2013

M.Sc. Organic Chemistry

Université Grenoble Alpes, France

2008-2010

B.Sc. Chemistry

Université Grenoble Alpes, France

2005-2008

 

 

Research Experience

 

Postdoc

present

Oct. 2015

Total Synthesis of Lactacystin and Salinosporamide A

DCM, Université Grenoble Alpes, France

Advisor: Prof. Jean-François Poisson

 

Scientist

Aug. 2015

May 2015

Research and Development of Novel Pharmaceutical Agents

Paraza Pharma Inc., Montreal, Canada

 

Postdoc

April. 2015

Dec. 2013

Total Synthesis of Triptolide by Gold-Catalyzed Photoredox Cyclization

CCRI, University of Ottawa, Canada

Advisor: Prof. Louis Barriault

 

Ph.D.

Nov. 2013

Oct. 2010

The Petasis Reaction for the Synthesis of Enantiopure Cyclic Compounds

ICSN CNRS, Gif-sur-Yvette, France                                                          open access link

Advisors: Prof. Jean-Marie Beau and Dr. Stéphanie Norsikian

 

M.Sc.

Jan.-June

2010

Toward the Total Synthesis of Hyacinthacine C1, a Natural Alkaloid

DCM, Université Grenoble Alpes, France

Advisors: Prof. Andrew Greene and Dr. Philippe Delair

 

M.Sc.

Mar.-June

2009

Synthesis of Aminoglycosides for Chiral Chromatography

DPM, Université Grenoble Alpes, France

Advisor: Dr. Isabelle Baussanne

 

B.Sc.

Jan.-Feb.

2008

Synthesis of Antimalarial Compounds

DPM, Université Grenoble Alpes, France

Advisor: Dr. Yung-Sing Wong

 

 

Publications

 

7) Gold-Catalyzed Photoredox C(sp2) Cyclization: Formal Synthesis of (±)-Triptolide. Cannillo, A.; Schwantje, T. R.; Bégin, M.; Barabé, F.; Barriault, L. Org. Lett. 2016, 18, 2592-2595 link

 

6) Persulfate-Enabled Direct C–H Alkylation of Heteroarenes with Unactivated Ethers. McCallum, T.; Jouanno, L.-A.; Cannillo, A.; Barriault, L. Synlett 2016, 27, 1282-1286 link

highlighted in Synfacts 2016, 12, 783 link

 

5) Indole Functionalization via Photoredox Gold Catalysis. Kaldas, S. J.; Cannillo, A.; McCallum, T.; Barriault, L. Org. Lett. 2015, 17, 2864-2866 link

 

4) Synthesis of Enantioenriched 1,2-trans-Diamines using the Borono-Mannich Reaction with N-protected α-Amino Aldehydes. Norsikian, S.; Beretta, M.; Cannillo, A.; Martin, A.; Retailleau, P.; Beau, J.‑M. Chem. Commun. 2015, 51, 9991-9994 link

 

3) From Enantiopure Hydroxyaldehydes to Complex Heterocyclic Scaffolds: Development of Domino Petasis/Diels-Alder and Cross-Metathesis/Michael Addition reactions. Cannillo, A.; Norsikian, S.; Tran Huu Dau, M.-E.; Retailleau, P.; Iorga, B.; Beau, J.‑M. Chem. Eur. J. 2014, 20, 12133–12143. link

 

2) Fast Synthesis of Complex Enantiopure Heterocyclic Scaffolds by a Tandem Sequence of Simple Transformations on Alpha-Hydroxy Aldehydes. Cannillo, A.; Norsikian, S.; Retailleau, P.; Tran Huu Dau, M.-E.; Iorga, B.; Beau, J.-M. Chem. Eur. J. 2013, 19, 9127–9131. link

 

1) Remarkable Stereoselectivity in Intramolecular Borono-Mannich Reactions: Synthesis of Conduramines. Norsikian, S.; Soulé, J.-F.; Cannillo, A.; Guillot, R.; Tran Huu Dau, M.-E.; Beau, J.-M. Org. Lett. 2012, 14, 544–547. link

 

 

Posters and Oral Communications

 

  • GA DCM, Grenoble (FR)

         July 2016

From Cyclobutanes to Natural Products: Total Synthesis of Lactacystin                                                                            talk

 

  • ISHC, Ottawa (CA)

July 2014

Total Synthesis of Triptolide by Gold-Catalyzed Photoredox Cyclization                                                     poster

 

  • JCO, Palaiseau (FR)

Sept. 2013

Double Domino Sequence for the Synthesis of Enantiopure Heterocyclic Scaffolds                              poster

 

  • SFST3, Grenoble (FR)

May 2013

Domino Petasis Diels-Alder Reaction: Fast Synthesis of Enantiopure Polycyclic Compounds                              poster

 

  • JED, Orsay (FR)

Sept. 2012

Domino Petasis Diels-Alder Reaction for the Synthesis of Enantiopure Polycyclic Molecules                                      talk

 

  • ISACS7, Edinburgh (UK)

June 2012

Intramolecular Petasis Reaction: Synthesis of Conduramines                                                                      poster

 

  • SFST2, Paris (FR)

June 2012

Intramolecular Petasis Reaction: Synthesis of Conduramines                                                                      poster

 

 

Teaching Experience

 

Teaching Assistant

Université Paris Sud, France

2011-2013

  • Laboratory classes of organic chemistry, B.Sc. level (96 h)
  • Tutorial classes of organic chemistry and electrochemistry, B.Sc. level (32 h)

 

 

Mentoring Experience

 

  • M.Sc. student working on synthesis of Lactacystin (6 months)

2016

  • B.Sc. students working on photoredox catalysis (2 x 4 months)

2014

  • B.Sc. student working on boronic acids synthesis (3 months)

2013

  • High school students working on precursors synthesis (2 weeks)

2012

 

 

Miscellaneous

 

  • Labex ARCANE postdoctoral fellowship

2015-2016

  • Destination 2020 postdoctoral fellowship

2013-2015

  • New Journal of Chemistry poster prize at SFST3 link

May 2013

  • ICSN Ph.D. scholarship

2010-2013

  • Member of the student council of ICSN

2010-2013

  • M.Sc. degree with magna cum laude

2010